Heliocidaris erythrogramma is a direct-developing sea urchin that has developed a modified ontogeny, a lowered larval skeleton, and accelerated improvement of the grownup skeleton. The Orthopedia gene (Otp) encodes a homeodomain transcription issue essential in patterning the larval skeleton of indirect-developing sea urchins. We examine the function of Otp in larvae of the indirect-developing sea urchin Heliocidaris tuberculata and its direct-developing congener H. erythrogramma. Otp is a single-copy gene with an an identical protein sequence in these species.
Expression of Otp is initiated by the late gastrula, initially in two cells of the oral ectoderm in H. tuberculata. These cells are restricted to oral ectoderm and exhibit left-right symmetry. There are about 266 copies of Otp mRNA per Otp- expressing cell in H. tuberculata. We examined OTP perform in H. tuberculata and H. erythrogramma embryos by microinjection of Otp mRNA. Mis-expression of Otp mRNA in H. tuberculata radialized the embryos and brought about defects throughout larval skeletogenesis.
Mis-expression of Otp mRNA in H. erythrogramma embryos didn’t have an effect on skeleton formation. This is in line with the commentary by in situ hybridization of no focus of Otp transcript in any explicit cells or area of the H. erythrogramma larva, and measurement of a stage of lower than one copy of endogenous Otp mRNA per cell in H. erythrogramma. OTP performs an essential function in patterning the larval skeleton of H. tuberculata, however this function apparently has been misplaced in the evolution of the H. erythrogramma larva, and changed by a brand new patterning mechanism.
In the sea urchin embryo skeletogenesis is the end result of a fancy sequence of molecular and mobile occasions that coordinate the morphogenetic course of. Past and up to date proof strongly point out that skeletal initiation and progress are strictly depending on indicators emanating from the oral ectodermal wall. As beforehand recommended, Orthopedia (Otp), a homeodomain-containing transcription issue particularly expressed in a small subset of oral ectoderm cells, is perhaps implicated in this signalling pathway. In this examine, we make the most of three totally different methods to deal with the subject of whether or not Otp is an upstream regulator of sketelogenesis.
We describe the results of microinjection of Otp morpholino-substituted antisense oligonucleotides and dominant-negative Otp-engrailed mRNA in Paracentrotus lividus embryos. We display that inhibition of Otp expression fully abolishes skeletal synthesis. By distinction, coinjection of Otp mRNA and the morpholino antisense oligonucleotide particularly rescues the skeletogenic program. In addition, localized ectodermal expression of the Otp-GFP fusion gene assemble pushed by the hatching enzyme promoter, induces ectopic and irregular spiculogenesis. We additional present that an oblique goal of this homeoprotein is the skeletogenic particular gene SM30, whose expression is understood to be beneath the strict management of the oral ectoderm territory. Based on these outcomes, we conclude that Otp triggers the ectoderm-specific sign that promotes skeletogenesis.
Novel and conserved roles for orthodenticle/ otx and orthopedia/ otp orthologs in the gastropod mollusc Patella vulgata.
The orthodenticle/ otx and orthopedia/ otp courses of homeobox gene households have been recognized in all three main courses of bilaterians: deuterostomes, lophotrochozoans, and ecdysozoans. Otx genes have been studied extensively and play a job in the improvement of anterior neural constructions. Otp genes have been discovered to be concerned in nervous system improvement in mouse and Drosophila. To date, no members of these genes are identified in molluscs.
We cloned orthologs of orthodenticle/ otx and orthopedia/ otpfrom the gastropod Patella vulgata, and designated them Pv-otx and Pv-otprespectively. Our evaluation of the spatio-temporal expression sample of otx and otp orthologs throughout P. vulgata embryogenesis results in the following conclusions. First, Pv-otx is expressed in and round the stomodaeum and our evaluation thus helps the beforehand recommended conservation of the protostome and deuterostome larval mouth areas.
Second, we discover that Pv-otp is concerned in the improvement of the larval apical sensory organ, suggesting a conserved function for this gene household in nervous system improvement. The same conserved function in nervous system improvement has been proposed for orthodenticle/otx genes and we recommend that half of the cells expressing Pv-otx are concerned in the improvement of the anterior nervous system. Last, we postulate that otx genes have been ancestrally concerned in the improvement of ciliary bands in bilaterians.
Brachyury proteins regulate goal genes via modular binding websites in a cooperative style.
Brachyury proteins, a conserved subgroup of the T area transcription components, specify intestine and posterior mesoderm derivatives all through the animal kingdom. The T area confers DNA-binding properties to Brachyury proteins, however little is understood how these proteins regulate their goal genes. We characterised a direct goal gene of the Drosophila Brachyury-homolog Brachyenteron. Brachyenteron prompts the homeobox gene orthopedia in a dose-dependent method through a number of binding websites with the consensus. The websites and their A/T-rich flanking areas are conserved between D. melanogaster and Drosophila virilis.
 Alpha-bungarotoxin CF488a |
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| 9-00005 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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 Alpha-bungarotoxin, CF568 |
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| 9-00006 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin, CF568 |
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| 9-00006 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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 Alpha-bungarotoxin, CF594 |
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| 9-00007 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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 Alpha-bungarotoxin CF594 |
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| 9-00007 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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 Alpha-bungarotoxin, CF633 |
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| 9-00009 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-bungarotoxin, CF633 |
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| 9-00009 | Biotium |
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Description: Minimum order quantity: 1 unit of 100uG |
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 Alpha-bungarotoxin |
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| 00010-1 | Biotium | 1MG | EUR 168 |
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Description: Minimum order quantity: 1 unit of 1MG |
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 Fluorescein-Alpha-bungarotoxin |
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| 00011 | Biotium | 500uG | EUR 367 |
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Description: Minimum order quantity: 1 unit of 500uG |
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 Tetramethylrhodamine-Alpha-bungarotoxin |
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| 00012 | Biotium | 500uG | EUR 383 |
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Description: Minimum order quantity: 1 unit of 500uG |
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) Fluorescein-alpha-bungarotoxin: (10x50ug) |
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| 00013 | Biotium | 10ST | EUR 417 |
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Description: Minimum order quantity: 1 unit of 10ST |
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) Tetramethylrhodamine-alpha-bungarotoxin: (10x50ug) |
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| 00014 | Biotium | 10ST | EUR 466 |
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Description: Minimum order quantity: 1 unit of 10ST |
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: (500ug)) Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (500ug) |
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| 00015 | Biotium | 500uG | EUR 466 |
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Description: Minimum order quantity: 1 unit of 500uG |
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: (10x50ug)) Sulforhodamine 101-a-bungarotoxin (Texas Red--a-bungarotoxin): (10x50ug) |
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| 00016 | Biotium | 10ST | EUR 523 |
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Description: Minimum order quantity: 1 unit of 10ST |
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 Biotin-xx-a-bungarotoxin |
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| 00017 | Biotium | 500uG | EUR 433 |
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Description: Minimum order quantity: 1 unit of 500uG |
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 Alpha-Bungarotoxin, CF555 conjugate |
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| 9-00018 | Biotium |
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Description: Minimum order quantity: 1 unit of 500uG |
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Alpha-Bungarotoxin, CF555 conjugate |
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| 9-00018 | Biotium |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Biotin-cAMP, diisopropylethylammonium salt: |
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| 00020 | Biotium | 1MG | EUR 314 |
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Description: Minimum order quantity: 1 unit of 1MG |
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) Biotin-cAMP, diisopropylethylammonium salt: (20x50ug) |
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| 00020-1 | Biotium | 20ST | EUR 418 |
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Description: Minimum order quantity: 1 unit of 20ST |
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 Biotin-cGMP, diisopropylethylammonium salt: |
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| 00021 | Biotium | 1MG | EUR 344 |
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Description: Minimum order quantity: 1 unit of 1MG |
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) Biotin-cGMP, diisopropylethylammonium salt: (20x50ug) |
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| 00021-1 | Biotium | 20ST | EUR 448 |
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Description: Minimum order quantity: 1 unit of 20ST |
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 Cyanine 644-cAMP: |
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| 00022 | Biotium | 1MG | EUR 491 |
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Description: Minimum order quantity: 1 unit of 1MG |
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) Cyanine 644-cAMP: (20x50ug) |
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| 00022-1 | Biotium | 20ST | EUR 625 |
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Description: Minimum order quantity: 1 unit of 20ST |
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 Fluorescein Methotrexate, triammonium salt: |
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| 00023 | Biotium | 1MG | EUR 281 |
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Description: Minimum order quantity: 1 unit of 1MG |
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 Staurosporine |
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| 00025 | Biotium | 100uG | EUR 139 |
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Description: Minimum order quantity: 1 unit of 100uG |
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 Alpha-bungarotoxin, CF543 |
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| 00026 | Biotium | 500uG | EUR 494 |
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Description: Minimum order quantity: 1 unit of 500uG |
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 Rhodamine phalloidin 300u |
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| 00027 | Biotium | 300 | EUR 345 |
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Description: Minimum order quantity: 1 unit of 300 |
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 Biotin-xx-phalloidin |
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| 00028 | Biotium | 100U | EUR 428 |
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Description: Minimum order quantity: 1 unit of 100U |
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 Fluorescein-phalloidin |
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| 00030 | Biotium | 300U | EUR 345 |
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Description: Minimum order quantity: 1 unit of 300U |
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 Rhodamine 110 phalloidin |
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| 00032 | Biotium | 300ST | EUR 345 |
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Description: Minimum order quantity: 1 unit of 300ST |
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 Phalloidin) Sulforhodamine 101 (Texas-Red) Phalloidin |
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| 00033 | Biotium | 300EU | EUR 345 |
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Description: Minimum order quantity: 1 unit of 300EU |
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 Phalloidin, CF405M |
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| 00034 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF405M |
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| 00034-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 CF488A-cAMP |
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| 00036 | Biotium | 100ug | EUR 172 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 CF640R-cAMP |
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| 00037 | Biotium | 100ug | EUR 172 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Phalloidin, CF555 |
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| 00040 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF555 |
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| 00040-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF647 |
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| 00041 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF647 |
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| 00041-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF488A |
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| 00042 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF488A |
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| 00042-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF543 |
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| 00043 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF543 |
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| 00043-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF568 |
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| 00044 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF568 |
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| 00044-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF594 |
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| 00045 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF594 |
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| 00045-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF633 |
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| 00046 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF633 |
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| 00046-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF660R |
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| 00047 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF660R |
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| 00047-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF680R |
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| 00048 | Biotium | 300U | EUR 466 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF680R |
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| 00048-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF350 |
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| 00049 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF350 |
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| 00049-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF640R |
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| 00050 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF640R |
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| 00050-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF532 |
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| 00051 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF532 |
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| 00051-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF660C |
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| 00052 | Biotium | 300U | EUR 442 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF660C |
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| 00052-T | Biotium | 50U | EUR 133 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF680 |
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| 00053 | Biotium | 300U | EUR 466 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF680 |
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| 00053-T | Biotium | 50U | EUR 147 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF430 |
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| 00054 | Biotium | 300U | EUR 449 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF430 |
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| 00054-T | Biotium | 50U | EUR 139 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Phalloidin, CF440 |
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| 00055 | Biotium | 300U | EUR 449 |
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Description: Minimum order quantity: 1 unit of 300U |
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Phalloidin, CF440 |
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| 00055-T | Biotium | 50U | EUR 139 |
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Description: Minimum order quantity: 1 unit of 50U |
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 Cholera Toxin Subunit B, CF488A conjugate |
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| 00070 | Biotium | 100ug | EUR 261 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF568 conjugate |
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| 00071 | Biotium | 100ug | EUR 261 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF594 conjugate |
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| 00072 | Biotium | 100ug | EUR 261 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF640R conjugate |
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| 00073 | Biotium | 100ug | EUR 264 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF532 conjugate |
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| 00074 | Biotium | 100ug | EUR 264 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF543 conjugate |
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| 00075 | Biotium | 100ug | EUR 264 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF620R conjugate |
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| 00076 | Biotium | 100ug | EUR 264 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF633 conjugate |
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| 00077 | Biotium | 100ug | EUR 264 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF660R conjugate |
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| 00078 | Biotium | 100ug | EUR 264 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Cholera Toxin Subunit B, CF680R conjugate |
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| 00079 | Biotium | 100ug | EUR 282 |
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Description: Minimum order quantity: 1 unit of 100ug |
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 Human Transferrin, CF488A conjugate |
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| 00081 | Biotium | 1mg | EUR 149 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 Human Transferrin, CF543 conjugate |
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| 00082 | Biotium | 1mg | EUR 149 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 Human Transferrin, CF568 conjugate |
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| 00083 | Biotium | 1mg | EUR 149 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 Human Transferrin, CF594 conjugate |
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| 00084 | Biotium | 1mg | EUR 149 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 Human Transferrin, CF640R conjugate |
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| 00085 | Biotium | 1mg | EUR 149 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 Human Transferrin, CF680R conjugate |
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| 00086 | Biotium | 1mg | EUR 149 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 Human Transferrin, CF750 conjugate |
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| 00087 | Biotium | 1mg | EUR 155 |
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Description: Minimum order quantity: 1 unit of 1mg |
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 HIV-1 tat recombinant antigen |
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| 00110-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HIV-1 tat recombinant antigen full length 15 kDa |
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HIV-1 tat recombinant antigen |
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| 00110-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HIV-1 tat recombinant antigen full length 15 kDa |
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 HIV-1 GAG P24 Recombinant Antigen |
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| 00111-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa |
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HIV-1 GAG P24 Recombinant Antigen |
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| 00111-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HIV-1 gag p24 recombinant antigen a.a 77 to a.a 436 of the HIV-1 gag region 39 kDa |
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 HIV-1 nef recombinant antigen |
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| 00112-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa |
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HIV-1 nef recombinant antigen |
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| 00112-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HIV-1 nef recombinant antigen a.a 3 to a.a 190 of the HIV-1 nef region 20 kDa |
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 HIV-1 env gp41 recombinant antigen |
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| 00113-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HIV-1 env gp41 recombinant antigen a.a 466 to a.a 753 of the HIV-1 env region 32 kDa |
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HIV-1 env gp41 recombinant antigen |
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| 00113-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HIV-1 env gp41 recombinant antigen a.a 466 to a.a 753 of the HIV-1 env region 32 kDa |
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 HIV-2 GP 36 Recombinant Antigen |
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| 00114-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HIV -2 env gp36 recombinant antigen a.a 390 to a.a 702 of the HIV-2 env region 34 kDa |
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HIV-2 GP 36 Recombinant Antigen |
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| 00114-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HIV -2 env gp36 recombinant antigen a.a 390 to a.a 702 of the HIV-2 env region 34 kDa |
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 HCV core recombinant antigen |
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| 00115-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa |
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HCV core recombinant antigen |
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| 00115-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa |
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 HCV core recombinant antigen, Biotin conjugate |
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| 00115-V-B-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Biotin conjugate. |
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HCV core recombinant antigen, Biotin conjugate |
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| 00115-V-B-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Biotin conjugate. |
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 HCV core recombinant antigen, FITC conjugate |
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| 00115-V-F-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Fluorescein conjugate. |
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HCV core recombinant antigen, FITC conjugate |
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| 00115-V-F-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa. Fluorescein conjugate. |
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 HCV core recombinant antigen, Rhodamine |
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| 00115-V-R-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa . Rhodamine conjugate. |
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HCV core recombinant antigen, Rhodamine |
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| 00115-V-R-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core recombinant antigen a.a 2 to a.a 192 of HCV polyprotein 22 kDa . Rhodamine conjugate. |
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 HCV NS4 recombinant antigen NS4a+b |
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| 00116-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. |
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HCV NS4 recombinant antigen NS4a+b |
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| 00116-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. |
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 HCV NS4 recombinant antigen NS4a+b, Biotin |
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| 00116-V-B-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate. |
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HCV NS4 recombinant antigen NS4a+b, Biotin |
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| 00116-V-B-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Biotin conjugate. |
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 HCV NS4 recombinant antigen NS4a+b, FITC |
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| 00116-V-F-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Fluorescein conjugate. |
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HCV NS4 recombinant antigen NS4a+b, FITC |
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| 00116-V-F-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Fluorescein conjugate. |
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 HCV NS4 recombinant antigen NS4a+b, Rhodamine |
|||
| 00116-V-R-01mg | Virogen | 0,1 mg | EUR 267.5 |
|
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Rhodamine conjugate. |
|||
HCV NS4 recombinant antigen NS4a+b, Rhodamine |
|||
| 00116-V-R-1000ug | Virogen | 1000 ug | EUR 1282.5 |
|
Description: HCV NS4 recombinant antigen NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein, 19 kDa. Rhodamine conjugate. |
|||
 HCV NS3 recombinant antigen |
|||
| 00117-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
|
Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa |
|||
HCV NS3 recombinant antigen |
|||
| 00117-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
|
Description: HCV NS3 recombinant antigen a.a 1400 to a.a 1643 of HCV polyprotein 22 kDa |
|||
 HBV core recombinant antigen |
|||
| 00120-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
|
Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa |
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HBV core recombinant antigen |
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| 00120-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 183 of HBV core antigen 18 kDa |
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 HBV core recombinant antigen, Delta |
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| 00121-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 144 of HBV core antigen 16 kDa |
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HBV core recombinant antigen, Delta |
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| 00121-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HBV core recombinant antigen HBcAg a.a 1 to a.a 144 of HBV core antigen 16 kDa |
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 HBV surface recombinant antigen HBsAg |
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| 00122-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant |
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HBV surface recombinant antigen HBsAg |
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| 00122-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant |
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 HBV surface recombinant antigen HBsAg antigen |
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| 00123-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity |
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HBV surface recombinant antigen HBsAg antigen |
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| 00123-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity |
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HBV surface recombinant antigen HBsAg antigen |
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| 00124-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant |
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HBV surface recombinant antigen HBsAg antigen |
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| 00124-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant |
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 ORF2 recombinant antigen) HEV (Birma) ORF2 recombinant antigen |
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| 00131-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HEV (Birma) ORF2 recombinant antigen a.a. 633 to a.a 659. |
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HEV (Birma) ORF2 recombinant antigen |
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| 00131-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HEV (Birma) ORF2 recombinant antigen a.a. 633 to a.a 659. |
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HEV (Birma) ORF2 recombinant antigen |
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| 00132-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HEV (Birma) ORF2 recombinant antigen a.a. 403 to a.a 461. |
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HEV (Birma) ORF2 recombinant antigen |
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| 00132-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HEV (Birma) ORF2 recombinant antigen a.a. 403 to a.a 461. |
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 AA 403-461 HEV Birma ORF2 Recombinant Antigen |
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| 00133-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HEV (Birma) ORF2 recombinant antigen a.a. 92 to a.a 123. |
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AA 403-461 HEV Birma ORF2 Recombinant Antigen |
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| 00133-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HEV (Birma) ORF2 recombinant antigen a.a. 92 to a.a 123. |
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 T, Pallidum recombinant antigen p15 |
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| 00141-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: T. Pallidum recombinant antigen p15 (full length) |
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T, Pallidum recombinant antigen p15 |
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| 00141-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: T. Pallidum recombinant antigen p15 (full length) |
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 T, Pallidum recombinant antigen p17 |
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| 00142-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: T. Pallidum recombinant antigen p17 (full length) |
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T, Pallidum recombinant antigen p17 |
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| 00142-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: T. Pallidum recombinant antigen p17 (full length) |
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 T, Pallidum recombinant antigen p45 |
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| 00143-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: T. Pallidum recombinant antigen p45 (full length) |
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T, Pallidum recombinant antigen p45 |
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| 00143-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: T. Pallidum recombinant antigen p45 (full length) |
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 T, pallidum recombinant antigen TmpA |
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| 00144-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: T. Pallidum recombinant antigen TmpA (full length) |
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T, pallidum recombinant antigen TmpA |
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| 00144-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: T. Pallidum recombinant antigen TmpA (full length) |
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 HCV core 2-119aa recombinant antigen |
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| 00150-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core 2-119aa recombinant antigen. Genotypes available: 1a, 1b, 2a, 2b, 3a, 3b, 3/10, 4, 5, 6a |
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HCV core 2-119aa recombinant antigen |
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| 00150-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core 2-119aa recombinant antigen. Genotypes available: 1a, 1b, 2a, 2b, 3a, 3b, 3/10, 4, 5, 6a |
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 HCV Core 24 Antigen |
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| 00151-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core 24 antigen. |
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HCV Core 24 Antigen |
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| 00151-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core 24 antigen. |
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HCV core recombinant antigen |
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| 00152-V-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: HCV core recombinant antigen a.a.105-302 |
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HCV core recombinant antigen |
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| 00152-V-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: HCV core recombinant antigen a.a.105-302 |
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Reporter assays and site-directed mutagenesis display that Brachyenteron binding websites confer in half additive, in half synergistic results on otp transcription ranges. This suggests an interplay of Brachyenteron proteins on the DNA, which we may map to a conserved motif inside the T area. Mouse Brachyury additionally interacts with Brachyenteron via this motif. We additional present that the Xenopus and mouse Brachyury homologs activate orthopedia expression when expressed in Drosophila embryonic cells. We suggest that the mechanisms to realize goal gene expression via variable binding websites and thru outlined protein-protein interactions is perhaps conserved for Brachyury kin.